应用
2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. It is also used in the synthesis of EGFR inhibitors.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.

基本信息

MDL
MFCD03788200

EINECS
000-000-0

分子式
C₄HCl₃N₂

分子量
183.43

沸点
84°/1mm

闪点
>110°(230°F)

密度
1.600

折射率
1.5730

灵敏度
Ambient temperatures.

溶解性
Not miscible or difficult to mix in water.

Beilstein
4449

GHS危害和防范说明

GHS符号

Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
34
Causes burns.

安全等级
20-23-26-36/37/39-45
When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

欧盟危险品标志

TSCA
否