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睾丸特异激酶底物蛋白抗体
产品名称 Anti-Tsks Anti-testis-specific serine kinase substrate Antibody 产品介绍
靶标: Tsks 产品别名: Stk22s1; Tssks1; Tsks; testis-specific serine kinase substrate; testis-specific serine kinase substrate; testis-specific serine kinase substrate; STK22 substrate 1; clone 4; serine/threonine kinase 22 substrate 1; testis-specific kinase substrate; testis-specific serine/threonine kinase substrate 1; 睾丸特异激酶底物蛋白; 背景信息: TSKS is a 592 amino acid protein that is highly expressed in human testicular tissue. Low levels of TSKS are detectable in prostate, placenta, fetal liver, thymus, and mammary gland tissues. TSKS is found to be downregulated in cancerous testicular tissue from seminoma, teratocarcinoma, embryonal and Leydig cell tumors concurrently with high expression in neighboring premalignant carcinoma. TSKS protein contains an N-terminal signal peptide, but does not contain a transmembrane region. TSKS has many potential phosphorylation and glycosylation sites and is phosphorylated by soluble recombinant TSSK2 in vitro. It is thought that TSKS likely plays a physiological role in spermatogenesis or spermiogenesis. |
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